{"id":4518,"date":"2023-10-09T19:19:14","date_gmt":"2023-10-09T19:19:14","guid":{"rendered":"https:\/\/regtechafrica.com\/healthcare\/?p=4518"},"modified":"2023-10-09T19:19:14","modified_gmt":"2023-10-09T19:19:14","slug":"global-researchers-develop-single-dose-intranasal-vaccine-effective-against-measles-mumps-and-multiple-covid-variants","status":"publish","type":"post","link":"https:\/\/regtechafrica.com\/healthcare\/global-researchers-develop-single-dose-intranasal-vaccine-effective-against-measles-mumps-and-multiple-covid-variants\/","title":{"rendered":"Global: Researchers Develop Single-Dose Intranasal Vaccine Effective Against Measles, Mumps, and Multiple COVID Variants"},"content":{"rendered":"<p>In a recent study published in a <a href=\"https:\/\/www.pnas.org\/doi\/10.1073\/pnas.2220403120\" target=\"_blank\" rel=\"noopener\">scientific journal<\/a>, a team of researchers has created a trivalent intranasal vaccine called MMS, designed to provide immunity against measles, mumps, and various SARS-CoV-2 variants.<\/p>\n<p>This groundbreaking vaccine offers robust and long-lasting protection against significant strains of the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2).<\/p>\n<p>The research team&#8217;s approach was built upon the well-established safety and efficacy of the measles-mumps-rubella (MMR) vaccine platform.<\/p>\n<p>The COVID-19 pandemic, caused by the SARS-CoV-2 virus, has resulted in more than 6.96 million fatalities and over 771 million infections worldwide as of October 2023.<\/p>\n<p>Despite the development of numerous vaccines based on the prefusion spike (S) protein, these vaccines face challenges such as reduced effectiveness against evolving SARS-CoV-2 variants, short-lived immunity, and the absence of mucosal immunity.<\/p>\n<p>The emergence of various variants, notably the highly mutated Omicron strain, has posed challenges for current vaccines.<\/p>\n<p>Therefore, there is an urgent need for more effective vaccines. Given the ongoing emergence of SARS-CoV-2 variants and the limitations of existing vaccines, further research is crucial for the development of next-generation intranasal vaccines that can offer broader mucosal immunity and adaptability to evolving strains.<\/p>\n<p>The modified MMR vaccine induces strong immune responses both in systemic and lung-specific regions, providing protection against multiple SARS-CoV-2 strains, including the Delta and Omicron BA.1 variants.<\/p>\n<p>Unlike single-strain vaccines with limited protective capabilities, this trivalent vaccine demonstrates broad neutralization abilities against diverse virus strains.<\/p>\n<p>Administered intranasally, the MMS vaccine triggers robust immune responses throughout the body, including mucosal areas, potentially offering protection against SARS-CoV-2 variants.<\/p>\n<p>Crucially, the vaccine&#8217;s adaptable design allows for easy adjustments to address newly emerging variants.<\/p>\n<p>In summary, this next-generation COVID-19 vaccine candidate offers comprehensive and long-lasting protection, highlighting its potential as a significant tool against SARS-CoV-2 variants.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>In a recent study published in a scientific journal, a team of researchers has created a trivalent intranasal vaccine called MMS, designed to provide immunity against measles, mumps, and various&hellip;<\/p>\n","protected":false},"author":1,"featured_media":4520,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[73,80],"tags":[],"class_list":["post-4518","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-global","category-news"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"https:\/\/i0.wp.com\/regtechafrica.com\/healthcare\/wp-content\/uploads\/2023\/10\/Researchers-formulate-single-dose-intranasal-vaccine-for-measles-mumps-multiple-COVID-variants.jpg?fit=1200%2C675&ssl=1","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/regtechafrica.com\/healthcare\/wp-json\/wp\/v2\/posts\/4518","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/regtechafrica.com\/healthcare\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/regtechafrica.com\/healthcare\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/regtechafrica.com\/healthcare\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/regtechafrica.com\/healthcare\/wp-json\/wp\/v2\/comments?post=4518"}],"version-history":[{"count":1,"href":"https:\/\/regtechafrica.com\/healthcare\/wp-json\/wp\/v2\/posts\/4518\/revisions"}],"predecessor-version":[{"id":4521,"href":"https:\/\/regtechafrica.com\/healthcare\/wp-json\/wp\/v2\/posts\/4518\/revisions\/4521"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/regtechafrica.com\/healthcare\/wp-json\/wp\/v2\/media\/4520"}],"wp:attachment":[{"href":"https:\/\/regtechafrica.com\/healthcare\/wp-json\/wp\/v2\/media?parent=4518"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/regtechafrica.com\/healthcare\/wp-json\/wp\/v2\/categories?post=4518"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/regtechafrica.com\/healthcare\/wp-json\/wp\/v2\/tags?post=4518"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}