{"id":2855,"date":"2022-09-20T12:39:47","date_gmt":"2022-09-20T12:39:47","guid":{"rendered":"https:\/\/regtechafrica.com\/healthcare\/?p=2855"},"modified":"2022-09-20T12:39:47","modified_gmt":"2022-09-20T12:39:47","slug":"global-israeli-biotech-firm-plans-to-create-human-embryos-to-harvest-organs-field-experts-say-there-are-ethical-concerns","status":"publish","type":"post","link":"https:\/\/regtechafrica.com\/healthcare\/global-israeli-biotech-firm-plans-to-create-human-embryos-to-harvest-organs-field-experts-say-there-are-ethical-concerns\/","title":{"rendered":"Global: Israeli Biotech Firm Plans to Create Human Embryos to Harvest Organs, Field Experts Say There are Ethical Concerns"},"content":{"rendered":"<p>An Israeli biotech company that recently created mouse embryos using stem cells, has\u00a0announced plans to make human embryos to harvest tissue for organ transplants and anti-aging procedures. But an ethical scientist and stem cell expert with the Charlotte Lozier Institute told CBN News that these strides in stem cell research are a &#8220;real call for concern&#8221;.<\/p>\n<p>Renewal Bio is pursuing advances in stem-cell technology and artificial womb development with the help of Jacob Hanna, a biologist at the Weizmann Institute of Science in Rehovot.<\/p>\n<p>In a peer-reviewed scientific journal,\u00a0<a href=\"https:\/\/www.cell.com\/cell\/fulltext\/S0092-8674(22)00981-3\" target=\"_blank\" rel=\"noopener\">Cell<\/a>, Hanna explained that without the use of sperm, egg, or fertilization, stem cells placed in a Petri dish spontaneously joined together, outside of the womb, and assembled embryos with beating hearts, intestinal tracts, and brains.<\/p>\n<p>&#8220;Remarkably, we show that embryonic stem cells generate whole synthetic embryos, meaning this includes the placenta and yolk sac surrounding the embryo,&#8221; Hanna said. &#8220;We are truly excited about this work and its implications.&#8221;<\/p>\n<p>Hanna noted that the synthetic embryos were not &#8220;real&#8221; embryos and did not have the potential to develop into live animals. But that is partly because they don&#8217;t have the technology, right now, to do so. He did admit that the synthetic mouse embryos are &#8220;95% similar to normal mouse embryos.&#8221;<\/p>\n<p>&#8220;My contention would be the technique to create them may be synthetic, but if you have something growing [that has]\u00a0a beating heart and a nervous system and limbs and digits and other organs that look exactly like the organism you would take out of the womb, its an embryo,&#8221; Dr. David Prentice, Ph.D. from the\u00a0<a href=\"https:\/\/lozierinstitute.org\/\" target=\"_blank\" rel=\"noopener\">Charlotte Lozier Institute<\/a>\u00a0told CBN News.<\/p>\n<p>Prentice is the vice president and\u00a0<a href=\"https:\/\/lozierinstitute.org\/team-member\/david-prentice\/\" target=\"_blank\" rel=\"noopener\">research director<\/a>\u00a0at the Charlotte Lozier Institute and was a founding advisory board member for the Midwest Stem Cell Therapy Center, a unique comprehensive stem cell center in Kansas that he was instrumental in creating.<\/p>\n<p>He told CBN News that using the term synthetic to describe the embryos is misleading.<\/p>\n<p>&#8220;It&#8217;s being disingenuous to make us think that these are not actual organisms,&#8221; Prentice explained.<\/p>\n<p>&#8220;They&#8217;re coming up with new and different ways to make an embryo is the bottom line,&#8221; he noted. &#8220;And by calling it synthetic, you might say we are lulled into a false sense of security that &#8216;oh there not experimenting on embryos [and]\u00a0we don&#8217;t have any problems with them doing this with mice.&#8217; But as they&#8217;ve said in their papers they also want to do this with humans.&#8221;<\/p>\n<p>And Prentice is right about why the firm wants to advance its research.<\/p>\n<p>Hanna\u00a0<a href=\"https:\/\/www.technologyreview.com\/2022\/08\/04\/1056633\/startup-wants-copy-you-embryo-organ-harvesting\/\" target=\"_blank\" rel=\"noopener\">admits to<\/a>\u00a0taking his &#8220;ground-breaking&#8221; technology to the next level and creating human embryos. The purpose is to harvest tissue to be used in transplant treatments meant to lengthen a person&#8217;s life and health.<\/p>\n<p>He&#8217;s behind\u00a0<a href=\"https:\/\/www.renewal.bio\/\" target=\"_blank\" rel=\"noopener\">Renewal Bio<\/a>, a startup to make &#8220;humanity younger and healthier&#8221;.<\/p>\n<p>&nbsp;<\/p>\n<p>&#8220;The vision of the company is &#8216;can we use these organized embryo entities that have early organs to get cells that can be used for transplantation?&#8217; We view it as perhaps a universal starting point,&#8221; Hanna said.<\/p>\n<p>CBN News reached out to Renewal Bio for comment and CEO Omri Amirav-Drory, Ph.D. said they were &#8220;not really ready to speak too much about the company.&#8221;<\/p>\n<p>Hanna told\u00a0<a href=\"https:\/\/www.technologyreview.com\/2022\/08\/04\/1056633\/startup-wants-copy-you-embryo-organ-harvesting\/\" target=\"_blank\" rel=\"noopener\">MIT Technology Review<\/a>\u00a0they plan to grow human embryos that are the equivalent of a 40 to 50-day-old pregnancy or about two months old. It is an age Hanna considers to be &#8220;the best entity to make organs and proper tissue.&#8221;<\/p>\n<p>Those embryonic blood cells would then be collected, multiplied, and transferred to an individual to help with &#8220;infertility, genetic diseases, and longevity&#8221;, according to the\u00a0<a href=\"https:\/\/www.renewal.bio\/\" target=\"_blank\" rel=\"noopener\">company&#8217;s website<\/a>.<\/p>\n<p>&#8220;There&#8217;s a real call for concern here that whether they are making these the old fashion way with an egg and a sperm or they&#8217;re making it by mixing stem cells together,&#8221; Lozier explained. &#8220;You&#8217;re still talking about instrumental use of a human being to harvest their spare parts.&#8221;<\/p>\n<p>Other field experts contend that Hanna&#8217;s experiments are a step too far and not necessary.<\/p>\n<p>&#8220;It&#8217;s absolutely not necessary, so why would you do it?&#8221; Nicolas Rivron, a stem-cell scientist at the Institute of Molecular Biotechnology in Vienna said. He argues that scientists should only create &#8220;the minimal embryonic structure necessary&#8221; to yield cells of interest.<\/p>\n<p>Prentice pointed out to CBN News that there are more ethical ways to get the same kind of cells.<\/p>\n<p>&#8220;Something may be constructed or manufactured ethically and have an ethical source&#8230;and you could feel very good about your research because you haven&#8217;t crossed an ethical line until somebody says &#8216;well let&#8217;s use it this way&#8217;,&#8221; he explained.<\/p>\n<p>In his next set of experiments, Hanna plans to use his own blood or skin cells and those of his team as the starting point for human embryos.<\/p>\n<p>&#8220;It does raise a problem for the stem cell field in general and maybe scientists need to ask that question &#8216;should I do this experiment?&#8217; rather than &#8216;can I do this experiment?&#8217;,&#8221; Prentice said<\/p>\n","protected":false},"excerpt":{"rendered":"<p>An Israeli biotech company that recently created mouse embryos using stem cells, has\u00a0announced plans to make human embryos to harvest tissue for organ transplants and anti-aging procedures. But an ethical&hellip;<\/p>\n","protected":false},"author":1,"featured_media":2861,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[73,80],"tags":[],"class_list":["post-2855","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-global","category-news"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"https:\/\/i0.wp.com\/regtechafrica.com\/healthcare\/wp-content\/uploads\/2022\/09\/Israeli-Biotech-Firm-Plans-to-Create-Human-Embryos-to-Harvest-Organs-Field-Experts-Say-There-are-Ethical-Concerns.png?fit=1365%2C745&ssl=1","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/regtechafrica.com\/healthcare\/wp-json\/wp\/v2\/posts\/2855","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/regtechafrica.com\/healthcare\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/regtechafrica.com\/healthcare\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/regtechafrica.com\/healthcare\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/regtechafrica.com\/healthcare\/wp-json\/wp\/v2\/comments?post=2855"}],"version-history":[{"count":1,"href":"https:\/\/regtechafrica.com\/healthcare\/wp-json\/wp\/v2\/posts\/2855\/revisions"}],"predecessor-version":[{"id":2862,"href":"https:\/\/regtechafrica.com\/healthcare\/wp-json\/wp\/v2\/posts\/2855\/revisions\/2862"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/regtechafrica.com\/healthcare\/wp-json\/wp\/v2\/media\/2861"}],"wp:attachment":[{"href":"https:\/\/regtechafrica.com\/healthcare\/wp-json\/wp\/v2\/media?parent=2855"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/regtechafrica.com\/healthcare\/wp-json\/wp\/v2\/categories?post=2855"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/regtechafrica.com\/healthcare\/wp-json\/wp\/v2\/tags?post=2855"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}